Philip Stewart LOW,Andrea L. KASINSKI,Loganathan RANGASAMY,Venkatesh CHELVAM
申请号:
US16413940
公开号:
US20190298843A1
申请日:
2019.05.16
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention described herein pertains to ligand-ionophore conjugates, that may also comprise a linked therapeutic agent or imaging agent, and pharmaceutical compositions containing the conjugates. Also described are methods of using the conjugates for increasing the endosomal accumulation and escape of a therapeutic agent, or an imaging agent.