KÜHNERT, SVEN,MERLA, BEATRIX,KLESS, ACHIM,BAHRENBERG, GREGOR,SCHRÖDER, WOLFGANG
申请号：
ES10708140
公开号：
ES2484371T3
申请日:
2010.03.11
申请国别(地区):
ES
年份:
2014
代理人:
摘要：
2-mercapto-3-substituted aminopyridines of the general formula (1), wherein R 1 represents (C 1-6) alkyl, saturated or unsaturated, linear or branched, unsubstituted or substituted in a single or multiple form； C3-10 cycloalkyl or heterocyclyl, in each case saturated or unsaturated, unsubstituted or substituted in a single or multiple form； aryl or heteroaryl, in each case unsubstituted or substituted simply or multiplely； with the proviso that, when R 1 represents heterocyclyl, the heterocyclyl bond with the upper general structure takes place through a carbon atom of the heterocyclyl； R2 represents aryl or heteroaryl, in each case unsubstituted or substituted in a single or multiple form； Y is selected from the group consisting of - (CR9aR9b) -, S (>； = O) 2, S (>； = O), -S-, -O-, C (>； = O)； R3, R4, R5, R6a, R6b, R7a, R7b, R8a, R8b, R9a and R9b represent in each case, independently of each other, H； F； Cl； Br； I； NO2； CF3； CN； OH； OCF3； SH； SCF3； NH2； C1-6 alkyl, O-C1-6 alkyl, OC (>； = O) -C1-6 alkyl, S-C1-6 alkyl, NH (C1-6 alkyl), N (C1-6 alkyl) 2, NH-C (>； = O) -C1-6 alkyl, N (C (>； = O) -C1-6 alkyl) 2 or C (>； = O) -C1-6 alkyl, in each case saturated or unsaturated, linear or branched, unsubstituted or substituted in a single or multiple way； C3-7 cycloalkyl or heterocyclyl, in each case saturated or unsaturated, branched or unbranched, unsubstituted or substituted in a single or multiple form； R7a can form with R8a a cycloalkyl (C3-7) group, which can be saturated or unsaturated, unsubstituted or substituted in a single or multiple way； where the term "alkyl substituted" means the substitution of one or more hydrogen atoms, in each case independently of each other, by F； Cl； Br； I； NO2； CF3； CN； (C1-8) alkyl； heteroalkyl (C2-8)； aryl； heteroaryl； cycloalkyl (C3-10)； heterocyclyl； aryl, heteroaryl, (C3-10) cycloalkyl or heterocyclyl linked through a (C1-8) alkyl or a (C2-8) heteralkyl； CHO； C (>； = O) (C1-8) alkyl； C (>； = O) aryl； C (>； =
