FISCHETTI, Vincent, A.,SCHMITZ, Jonathan,GILMER, Daniel,EULER, Chad
申请号:
DK12773653
公开号:
DK2699253T3
申请日:
2012.04.20
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus , and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.