Daniel Gilmer;Chad Euler;Jonathan Schmitz;Vincent A. Fischetti
发明人:
Vincent A. Fischetti,Jonathan Schmitz,Daniel Gilmer,Chad Euler
申请号：
US14112963
公开号：
US20140072549A1
申请日:
2012.04.20
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus, and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided.
