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Microspheres of Hydrolysed Starch with Endogenous, Charged Ligands
专利权人:
Malin Malmsjö;Sten Peter Apell;Eddie Thordarson;Peter Fyhr
发明人:
Malin Malmsjö,Eddie Thordarson,Sten Peter Apell,Peter Fyhr
申请号:
US15620996
公开号:
US20180022833A1
申请日:
2017.06.13
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The resent invention relates to biodegradable microspheres having a diameter of 1-2000 μm comprising cross-linked hydrolysed starch onto which at least one type of ligand has been coupled via a carboxylic ester bond. The ligand shall be an endogenous, charged molecule with a molecular mass of less than 1000 Da comprising at least one additional carboxylic acid function in addition to the one utilised for coupling the ligand to the micro-sphere and/or at least one amine function. On average 0.05-1.5 ligands are coupled to each glucose moiety in the hydrolysed starch.
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