MALIN MALMSJ,EDDIE THORDARSON,Sten Peter APELL,PETER FYHR
申请号:
IN5604/CHENP/2012
公开号:
IN2012CN05604A
申请日:
2012.06.26
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
The present invention relates to biodegradable microspheres having a diameter of 10-2000 �m comprising cross-linked hydrolysed starch onto which at least one type of ligand has been coupled via a carboxylic ester bond. The ligand shall be an endogenous charged molecule with a molecular mass of less than 1000 Da comprising at least one additional carboxylic acid function in addition to the one utilised for coupling the ligand to the microsphere and/or at least one amine function. On average 0.05-1.5 ligands are coupled to each glucose moiety in the hydrolysed starch.