Bonnie L. Bassler,Wai-Leung Ng,Lark J. Perez,Jianping Cong,Martin F. Semmelhack
申请号：
US14381432
公开号：
US09573908B2
申请日:
2013.02.20
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Using a whole-cell high-throughput screen, eleven molecules were identified that activate V. cholerae quorum sensing (QS). Eight molecules are receptor agonists and three molecules are antagonists of LuxO, the central NtrC-type response regulator that controls the global V. cholerae QS cascade. Pro-QS molecules are used for the development of novel anti-infectives.
