HAYNES, BARTON F.,WIEHE, KEVIN J.,BONSIGNORI, MATTIA
申请号：
CA3039089
公开号：
CA3039089A1
申请日:
2017.10.03
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention is directed to methods to identify improbable mutations in the heavy or light chain variable domain of an antibody, methods to identify antigens which bind to antibodies comprising such improbable mutations, and methods of using such antigens to induce immune responses.
