INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE(INSERM);UNIVERSITE DE MONTPELLIER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人:
Frederic BIENVENU
申请号：
US16478633
公开号：
US20190345212A1
申请日:
2018.01.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The invention relates to a nucleic acid molecule comprising: a. a first region comprising a nucleic acid sequence coding M for the protein Cyclin D1, also called CCND1, said first region being controlled by means allowing the expression of said protein, and b. at least one second region, said second region comprising essentially a sequence from 14 to 59 nucleic acids, said second region corresponding to a transcribed region of a gene, said second region containing at least a genetic modification compared to the same region of the corresponding wild-type version of said gene, said second region being genetically isolated from the means allowing the expression of said protein such that said second region is not translated into a peptide.
