A sustained release apparatus including at least one sustained release, minitablet implant；the or each mini tablet implant includinga pharmaceutically active composition includingat least one pharmaceutically active component； anda carrier therefor, wherein the or each tablet implant is of thecoated tablet or covered rod type；the or each mini tablet implant being approximately 0.1 to 0.5 times thelength and/or diameter of a single immediate release tablet capable ofprovidingthe desired threshold blood level depending on the pharmaceutical activeselected, andhaving a payload of approximately 30% to 70% by weight of the totalpayload of an equivalent immediate release treatment conducted for anequivalentperiod；the sustained release apparatus providing, in use, zero order release ofpharmaceutical active.
