A safety transfusion catheter comprises a flexible retention tube (2) fitted over a metal guiding needle (1). The flexible retention tube (2) is provided with a needle handle (22 22) connected with it. The angle between the end (3) of the flexible retention tube (2) and its longitudinal axis or longitudinal tube wall is less than 90º.The cross section of the needle handle (22 22) has an outer contour line of a closed curve formed with a curve (5 25) intersecting a beeline (6 26). A further safety transfusion catheter comprises a flexible retention tube (39) fitted over a metal guiding needle (32), a transfusion connecting tube (38) in fluid communication with flexible retention tube (39) and a rubber casing cap (42) at the end of the flexible retention tube (39). The back end of the metal guiding needle (32) is in telescoping engagement with a hollow sleeve (31). The transfusion connecting tube (38) and flexible retention tube (39) form a T-shaped or an oblique Y-shaped structure. A safety protect sheath (514) shorter than the metal guiding needle (32) is provided at the end of the hollow sleeve (31). A spring (533) is provided between the end hub (34) of the metal guiding needle (32) and the front end of the hollow sleeve (31). A seesaw typed stop block (36) is provided in the hollow sleeve (31). A reset button (37) is provided on the portion of the hollow sleeve (31) having the seesaw typed stop block (36).