PURCELL NGAMBO, LISA,GRAHAM, NEIL,MURPHY, ANDREW J.,EVANS, ROBERT
申请号：
CA3014202
公开号：
CA3014202A1
申请日:
2017.02.17
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides methods for enhancing the efficacy and/or safety of a vaccine. In certain embodiments, the invention provides methods to increase or potentiate the immune response to a vaccine in a subject in need thereof. The methods of the present invention comprise administering to a subject in need thereof an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody in combination with said vaccine. In certain embodiments, the methods of the present invention are used to afford enhanced protection to an infectious disease such as whooping cough.
