Disclosed are a single X-ray source blood irradiation device and an irradiation method thereof, which are used in the technical field of blood irradiators, and the blood irradiation device comprises: a rack (1), and an X-ray tube (2) arranged on the rack (1), a blood bag receiver (3) arranged below the X-ray tube (2) and composed of a base plate (31), and an outer wall (32) and an inner wall (33)arranged on the base plate (31), and an annular blood bag holding cavity (34) enclosed between the outer wall (32) and the inner wall (33) and the blood bag holding cavity (34) is used to place the blood or blood products to be irradiated, the base plate (31) of the blood bag receiver (3) is movably arranged on the rack (1) through a rotating shaft, and the rotating shaft is connected to the output shaft of a rotating electric motor through a transmission part. The present blood irradiation device fully uses the X-rays generated by the X-ray tube (2), and improves the utilization efficiency and uses the rotating electric motor to make the blood bag receiver rotate back and forth, forcing the blood or blood products inside the blood bag to flow, and making the blood or blood products in various local areas to change positions, so as to improve the irradiation homogeneity of the blood or blood products.La présente invention concerne un dispositif dexposition du sang à une source de rayons X unique et une méthode dexposition à un rayonnement associée, qui sont utilisés dans le domaine technique des dispositifs dexposition du sang à un rayonnement, et ledit dispositif dexposition du sang à un rayonnement comprend : une crémaillère (1), et un tube à rayons X (2) disposé sur la crémaillère (1), un récepteur (3) de poche de sang disposé sous le tube à rayons X (2) et composé dune plaque de base (31), et dune paroi externe (32) et dune paroi interne (33) disposées sur la plaque de base (31), et une cavité annulaire (34) de support de poche de sang enserrée entre la paroi externe (32
