Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions

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专利权人:

Connaught Laboratories

发明人:

McMaster, Ronald P.

申请号：

AU2012227310

公开号：

AU2012227310B2

申请日:

2012.09.25

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

#$%^&*AU2012227310B220160915.pdf#####PURIFICATION OF POLYSACCHARIDE-PROTEIN CONJUGATE VACCINES BY ULTRAFILTRATION WITH AMMONIUM SULFATE SOLUTIONS 5 Abstract The present invention relates to the removal of unbound polysaccharides from conjugated polysaccharide-protein vaccines using the method of ultrafiltration whereby the diafiltration solution contains saturating levels of ammonium sulfate.

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