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Peptide-lipid constructs and their use in diagnostic and therapeutic applications
专利权人:
KODE BIOTECH LIMITED
发明人:
WEINBERG CRISTINA-SIMONA,BOVIN NICOLAI,HENRY STEPHEN MICHEAL
申请号:
NZ60235308
公开号:
NZ602353A
申请日:
2008.09.11
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is a method of effecting qualitative and quantitative changes in the levels of a peptide expressed at the surface of cells including the step of contacting the cells with a solution of a peptide-lipid construct of the structure F-S-L at a concentration and for a time and temperature sufficient to allow the construct to incorporate into the surface, where F is the peptide, S is a spacer covalently linking F to L via an oligomer of ethylene glycol, and L is a lipid selected from the group consisting of diacyl- and dialkylglycerolipids.
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