The present invention provides a compound that selectively blocks Nav1.7 for Nav1.5. That is, to provide a heterocyclic aromatic amide derivative represented by general formula (I) or its salt, which shows higher effectiveness against various diseases related to Nav1.7 such as pain, [In the formula, X 1 -X 2 are NC or CN, Y 1 , Y 2 , Y 3 and Y 4 are -CH 2 -, -CR 4a H- or -O- etc., Z 1 is -O- etc., Ring A is a monocyclic aromatic ring with 3 to 7 members, R 1a and R 1b are hydrogen atoms or halogen atoms, etc., R 2 is a hydrogen atom, etc., R 3a , R 3b and R 3c are hydrogen atoms or alternatively Substituted C 1 -C 6 haloalkyl, etc., R 4a , R 4b, and R 4c are C 1 -C 6 haloalkyl or C 1 -C 6 haloalkoxy, etc., which may also be substituted, R 5a is A hydrogen atom, etc., R 5a and R 5b together form -CH 2 O-, etc., R 6a and R 6b are hydrogen atoms, etc., n is 1 or 2].本案發明提供一種對於Nav1.5會選擇性阻礙Nav1.7之化合物。亦即，提供一種對疼痛等之Nav1.7相關之各種疾病顯示較高有效性之一般式(I)表示之雜環芳香族醯胺衍生物或其鹽，[式中，X1-X2為N-C或C-N，Y1、Y2、Y3及Y4為-CH2-、-CR4aH-或-O-等，Z1為-O-等，環A為3~7員之單環式芳香族環等，R1a及R1b為氫原子或鹵原子等，R2為氫原子等，R3a、R3b及R3c為氫原子或亦可經取代之C1-C6鹵烷基等，R4a、R4b及R4c為亦可經取代之C1-C6鹵烷基或C1-C6鹵烷氧基等，R5a為氫原子等，R5a及R5b一起形成-CH2O-等，R6a及R6b為氫原子等，n為1或2]。
