Provided are: a novel compound represented by formula (I) and having an Akt inhibitory activity and a cell proliferation inhibitory activity or a salt thereof and a medicinal agent useful for the prevention and/or treatment of cancer, which relies on the above-mentioned activities. [In the formula, R1 and R2 independently represent a hydrogen atom, a halogen atom, a hydroxyl group, an amino group, an alkyl group or the like R3 represents an aromatic hydrocarbon group, a saturated or unsaturated heterocyclic group R4 and R5 independently represent a hydrogen atom, a halogen atom, a hydroxyl group, an amino group, an alkyl group, an alkynyl group, a cycloalkyl group, an aromatic hydrocarbon group, a saturated or unsaturated heterocyclic group or the like and R6 represents a hydrogen atom, a halogen atom, an amino group, an alkyl group or the like, wherein each of the combination of R1 and R2, the combination of R4 and R5 and the combination of R5 and R6 may, in conjunction with an atom to which both of the variables bind, together form a ring, and wherein a case in which each of R4 and R5 represents a hydrogen atom is excluded.]本發明提供一種具有Akt抑制作用且具有細胞增殖抑制效果之新穎化合物。又,本發明提供一種基於Akt抑制作用而對該Akt所參與之疾病、尤其是癌之預防及/或治療有用之醫藥。一種化合物或其鹽,其以下述式(I)表示[式中,R1及R2相同或不同,為氫原子、Ra、或可經獨立之1~3個Ra取代之C1-C6烷基,或者R1及R2亦可與所鍵結之碳原子一併形成C3-C10環烷基(可經獨立之1~3個Rb取代);R3為可經獨立之1~3個Rc取代之C6-C14芳香族烴基、或可經獨立之1~3個Rc取代之4~10員之飽和或不飽和雜環基;R4及R5相同或不同,為氫原子,Ra,可經選自由Ra、可經獨立之1~3個Ra取代之C1-C6烷氧基、可經獨立之1~3個Rb取代之C3-C10環烷基、可經獨立之1~3個Rb取代之C6-C14芳香族烴基、及可經獨立之1~3個Rb取代之4~10員之飽和或不飽和雜環基所組成之群中的獨立之1~3個基取代之C1-C6烷基,可經獨立之1~3個Ra取代之C2-C6烯基,可經獨立之1~3個Ra取代之C2-C6炔基,可經獨立之1~3個Rb取代之C3-C10環烷基,可經獨立之1~3個Rb取代之C6-C14芳香族烴基,或可經獨立之1~3個Rb取代之4~10員之飽和或不飽和雜環基,或者R4及R5亦可與其等所鍵結之氮原子一併形成4~10員之飽和或不飽和雜環基(可經獨立之1~3個Rb取代);R6為氫原子、氘原子、鹵素原子、胺基、氰基、硝基、C1-C6烷基或C1-C6鹵化烷基,或者亦可與R5一併形成4~10員之飽和或不飽和雜環基(可經獨立之1~3個Rb取代);其中,排除R4及R5均為氫原子之情形]。
