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HUMANISED ANTIBODIES WITH ANTI -TUMOUR ACTIVITY
专利权人:
发明人:
KIENZLE NORBERT ALEXANDER,CLARKE ADAM WILLIAM,DOYLE ANTHONY GERARD,JENNINGS PHILIP ANTHONY,POLLARD MATTHEW
申请号:
IN3366/KOLNP/2011
公开号:
IN2011KN03366A
申请日:
2011.08.09
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present invention provides humanised antibodies and binding domains thereof with anti-tumour activity,In particular the humanised antibodies have specific binding to and direct killing of human colon tumour cells and display potent immune- mediated cytotoxic activity against human colon cancer cells in vitro using antibody-dependent cell-mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC) assays and in vivo using mouse tumour models.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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