Matthew D. Alexander,Gerald D. Artman, III,Gordon L. Bray,James Carmichael,Soraya Carrancio,Brian E. Cathers,Matthew D. Correa,Joshua Hansen,Courtney G. Havens,Timothy S. Kercher,Antonia Lopez-Girona
申请号：
US16430189
公开号：
US20190282567A1
申请日:
2019.06.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.
