CELGENE CORPORATION;ALEXANDER Matthew D.;CORREA Matthew D.;HANSEN Joshua;LOPEZ-GIRONA Antonia;BRAY Gordon L.;WONG Lilly L.;CARRANCIO Soraya;CARMICHAEL James;ARTMAN Gerald D. III;CATHERS Brian E.;HAVEN
发明人:
ALEXANDER Matthew D.,CORREA Matthew D.,HANSEN Joshua,LOPEZ-GIRONA Antonia,BRAY Gordon L.,WONG Lilly L.,CARRANCIO Soraya,CARMICHAEL James,ARTMAN Gerald D. III,CATHERS Brian E.,HAVENS Courtney G.,KERCHE
申请号:
IL27188920
公开号:
IL271889D0
申请日:
2020.01.07
申请国别(地区):
IL
年份:
2020
代理人:
摘要:
Provided herein is 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-1-yl)-3-fluorobenzonitrile, or an enantiomer, a mixture of enantiomers, a tautomer, or a pharmaceutically acceptable salt thereof, and methods for treating, preventing or managing multiple myeloma using such compounds. Also provided are pharmaceutical compositions comprising the compounds, and methods of use of the compositions.