Chronotherapeutic dosing can include receiving, using a processor, sensor data from a sensor for a user, wherein the sensor data is collected subsequent to the user starting a regimen for a medication, determining, using the processor, a biological marker from the sensor data, wherein the biological marker is correlated with the medication, and comparing, using the processor, the biological marker with an expected state of the biological marker based upon a dose time of the medication. Chronotherapeutic dosing can also include providing, using the processor, a notification indicating a result of the comparing.