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Pharmaceutical dosage form for oral administration of a bcl-2 family inhibitor
专利权人:
ABBOTT GMBH & CO. KG
发明人:
LIEPOLD BERND,KNOBLOCH MARTIN,PACKHAEUSER CLAUDIA,STEIGER NORBERT,KOSTELAC DRAZEN
申请号:
NZ59724110
公开号:
NZ597241A
申请日:
2010.06.08
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
IP No. 597241 The disclosure relates to a pharmaceutical dosage form which comprises a solid dispersion product comprising N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1- yl)methyl)piperazin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl) propyl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide or a salt, hydrate or solvate thereof, at least one pharmaceutically acceptable polymer, and at least one pharmaceutically acceptable solubilizer. The disclosure is further directed to processes for preparing the pharmaceutical dosage form and to use of the dosage form for treating proliferative disorders.
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