The present invention provides combination therapies that include the administration of a compound that is a PDE1 enzyme inhibitor and other compounds that are useful for treating a neurodegenerative disease such as, for example, Alzheimer's disease, Parkinson's disease, or Huntington's disease. Another aspect of the present invention is directed to the combined use of said compounds for the treatment of neurodegenerative diseases and / or cognitive disorders. The present invention also provides a pharmaceutical composition comprising the PDE1 enzyme inhibitor together with another compound useful for treating a neurodegenerative disease.本発明は、ＰＤＥ１酵素阻害剤である化合物及び例えば、アルツハイマー病、パーキンソン病、又はハンチントン病などの神経変性疾患の治療に有用な他の化合物の投与を含む併用療法を提供する。本発明の別な態様は、神経変性疾患及び／又は認知障害の治療のための、前記化合物の組み合わせた使用を対象とする。本発明は、前記ＰＤＥ１酵素阻害剤を、神経変性疾患の治療に有用な他の化合物と共に含む医薬組成物も提供する。
