PROBLEM TO BE SOLVED: To provide an autoinducer-2 inhibitor effective for prevention and/or treatment of infectious diseases such as a periodontal disease.SOLUTION: An autoinducer-2 inhibitor includes a compound expressed by any of formulae (1) to (3) as an active ingredient. In the formulae, R1 represents an alkyl group having 3 to 12 carbon atoms R2 represents H or an alkyl group having 1 to 12 carbon atoms, can be mutually bonded to an OH group bonded to a benzene ring and may form a ring and R3 and R4 each independently represents an alkyl group having 1 to 12 carbon atoms.COPYRIGHT: (C)2014,JPO&INPIT【課題】歯周病等感染症の予防・治療に有効なオートインデューサー-2阻害剤の提供。【解決手段】式(1)~(3)のいずれかで表される化合物を有効成分とする、オートインデューサー-2阻害剤。(R1はC3~12のアルキル基、R2はH又はC1~12のアルキル基を表し、ベンゼン環に結合するOH基と互いに結合して環を形成してもよい。R3及びR4はそれぞれ独立にC1~12のアルキル基を表す。)【選択図】なし