A substituted amide compound is useful as an active ingredient of a pharmaceutical composition, in particular a pharmaceutical composition for treating diseases caused by lysophosphatidic acid (LPA). The compound is of a formula:In this formula, A is an optionally substituted aryl, etc.； B is an optionally substituted 5-membered aromatic hetero ring group； X is a single bond or —(CRX1RX2)n—； n is 1, 2, 3, or 4； RX1 and RX2 are hydrogen, etc.； Y1 to Y5 are each CRY or N； each RY is hydrogen, etc.； R1 and R2 are hydrogen, etc.； m is 1, 2, or 3； R3 is hydrogen, etc.； and R4 is an optionally substituted lower alkyl, etc.
