COMPOUND, PHARMACEUTICAL COMPOSITION, USE OF A COMPOUND, AND METHODS FOR INHIBITING TRANSITIONAL LOWER ESOPHAGIC SPHERIC RELAXATION AND FOR THE TREATMENT OR PREVENTION OF GASTROESOPHAGIC REFLUX DISEASE, DENTAL DIAGNOSIS, AND DENTAL DISEASE

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专利权人:

ASTRAZENECA AB

发明人:

METHVIN ISAAC,ABDELMALIK SLASSI,LOUISE EDWARDS,PETER DOVE,TAO XIN,TOMISLAV STEFANAC

申请号：

BRPI0719155

公开号：

BRPI0719155A2

申请日:

2007.09.25

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

The present invention is directed to compounds of formula I: Wherein R1 to R5, X and Z are further defined in the description. The invention also relates to processes for the preparation of the compounds and to intermediates used in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.

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