SPOSÓB WYTWARZANIA PEMETREKSEDU I JEGO SOLI Z LIZYNĄ

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专利权人:

BERLIN-CHEMIE AG

发明人:

BONACCORSI FABRIZIO,CALVANI FEDERICO,PASQUI FRANCO

申请号：

PL13777144

公开号：

PL2882753T3

申请日:

2013.08.08

申请国别(地区):

PL

年份:

2017

代理人:

摘要：

The present invention refers to a process for the synthesis of pemetrexed and salts thereof, in particular to a lysine salt thereof, to said salt as such and to pharmaceutical compositions that comprise the same. Furthermore, the present disclosure also relates to a crystalline form of the synthesis intermediate pemetrexed diethyl ether and a crystalline form of the pemetrexed lysine salt.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/