The present disclosure relates to novel sulfonimidamide compounds and related compounds and their use in treating a disorder responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process.本發明係關於新穎磺醯脒(sulfonimidamide)化合物及相關化合物;以及其治療對調節諸如IL-1β及IL-18等細胞介素、調節NLRP3或抑制NLRP3或發炎過程之相關組分之活化有反應之病症的用途。