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METHOD FOR DETERMINING THE EXPRESSION OF MODIFICATION ACTIVITY ASSOCIATED WITH A CARRIER
专利权人:
Эпштейн Олег Ильич (RU)
发明人:
Эпштейн Олег Ильич (RU)
申请号:
RU2013111961/15
公开号:
RU2013111961A
申请日:
2013.03.18
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A method for determining the severity of modifying activity associated with a carrier acquired in the process of processing a starting material in the form of a multiple successive decrease in the concentration of the starting material using the carrier, which is manifested in the ability to directly change the physicochemical and / or biological properties of the starting material when exposed to it the specified carrier, characterized in that analytical methods determine the presence or absence of molecules of the original th substance in said medium, and is measured by analytical methods, one or more characteristic parameters of the starting material before and after the interaction with it said carrier, wherein the degree of activity is determined by modifying the amount of change in characteristic parameter relative edinitsah.2. A method according to claim 1, characterized in that, in the presence of molecules of the starting material in the modified solvent, before measuring the characteristic parameter of the starting material, when interacting with said carrier, the molecules of the starting material are removed from the latter. The method according to claim 1, characterized in that a liquid solvent is used as a carrier. A method according to claim 1 or 2, characterized in that a solid carrier is used as the carrier. The method according to claim 1 or 2, characterized in that the analytic methods additionally record the effect on the physicochemical properties of the starting material of an inactive carrier and / or other substance, which are processed by repeated serial dilution or trituration with1. Способ определения выраженности модифицирующей активности, ассоциированной с носителем, приобретенной в процессе технологической обработки исходного вещества в виде многократного последовательного уменьшения концентрации последнего с использованием носителя, которая проявляется в способности непосредственно изменять физико-химические и/или биологические свой
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