A system for energy delivery into a patient comprises imaging means configured to image the patient and provide an image signal an energy source (500, 510, 730, 900, 1100) and a processor configured to: receive the image signal, the image signal being related to a position of a blood vessel determine a three dimensional coordinate of the blood vessel based on the image signal and control the energy source based on the determined coordinate of the blood vessel. The energy source (500, 510, 730, 900, 1100) is configured to deliver ultrasound energy from external to the patient to multiple regions (1350, 1680) that contain one or more nerves, the one or more nerves being next to or around the blood vessel (1140, 1155, 1340).