Skead, Ben,Westwood, Robert,Londesbrough, Derek,Northern, Julian,Atherton, Chris
申请号：
AU2018213119
公开号：
AU2018213119A1
申请日:
2018.01.25
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The present invention relates to a process for preparing a compound of formula [I], said process comprising the steps of: formula [II]+formula [III]−>；formula [I] (i) forming a reaction mixture comprising (a) a compound of formula [II], (b) a compound of formula [III] and (c) 1,2-propanediol or polyethylene glycol, or a mixture thereof, and optionally (d) a base； (ii) heating said reaction mixture to a temperature of at least about 150°C to form a compound of formula [I]； (iii) isolating said compound of formula [I]； and (iv) optionally converting said compound of formula [I] into salt form； wherein: R
