Claim 1, characterized because it responds to a compound of formula (1): or a pharmaceutically acceptable Salt or acid anhydride boronico thereof, where a is 0, 1 or 2 p is Hydrogen or a blocking portion of the amino Group: ra1 is C1 - aliphatic C1 - 6, 6 - (fluoroalif\u00e1tico, M - (CH2) H2 - RB, (CH2) M - CH2 - NHC (= NR4) - and NH, - (CH2) M - CH2 - (R4) 2 - (CH2) M - CH2 - N (R4) with (R4) 2 - (CH2) M - (r6) n (CH R4) 2- (CH2) M - (R5) - OR5 CH or CH - (CH2) M - (R5) - RA2 SR5 each is independently Hydrogen, Aliphatic C1 C1 - 6, 6 - (CH2) fluoroalif\u00e1tico, M - CH2 - RB - (CH2) M - (CH2) - NHC - and NH = NR4), - (CH2) M - CH2 - (R4) 2 - (CH2) M - CH2 - N (R4) with (R4) - (CH2) 2, M CH (r6) n (R4) 2 - (CH2) M - (CH) OR5) - or - (CH2) M - ch (R5) and SR5 each is for Ma separate Hydrogen, - CN, - NO2,Or - S (o) 2 - R10 RB each is independently a monocyclic or bicyclic Ring system is replaced or not replaced each R4 is independently Hydrogen or a group aliphatic, aryl, heteroaryl or heteroc\u00edclilo replaced or not replaced or R4: Two on the same atom of nitrogen Taken together with the atom of nitrogenForm a ring heteroc\u00edclilo 4 to 8 members replaced or not replaced with, in addition to the nitrogen Atom, between 0 and 2 Ring heteroatoms selected independently between n, o, and S, each R5 is independently Hydrogen or a group aliphatic, aryl, heteroaryl, Heteroc\u00edclilo or substituted or unsubstituted R6: Each is independently an aliphatic Group, an aryl,Heteroaryl substituted or unsubstituted or substituted: every R10 is independently C1 - C6 - 10 6 aliphatic, aryl, or - N (R4) 2 M is 0, 1 or 2 Z1 and Z2 are each independently ariloxi, Hydroxy, alkoxy, or aralcoxi or Z1 and Z2 together form: a portion from a Build Agent Acid B Oronico.Reivindicacion 1: Un compuesto caracterizado porque responde a la formula (1): o una sal farmacéuticamente aceptable o un anhídrido de ácido boronico del mismo, donde: A es 0, 1 o 2 P es hidrogeno o una porcion bloqueant
