PROBLEM TO BE SOLVED: To provide a mixing method by which a speed of mixing a low dose medicinal agent with additives is increased and the homogeneity of the contents of the agent is increased when the low dose medicinal agent is mixed with the additives through a powder mixing process.SOLUTION: The mixing method for increasing the homogeneity of the content of the medicinal agent comprises mixing the agent with a fluidizing modifier (talc, light anhydrous silicic acid or the like) in advance, and subsequently mixing the mixed powder further with other additives.COPYRIGHT: (C)2003,JPO【課題】 低含有量の薬物と添加剤を粉体混合する場合において、薬物と添加剤の混合速度を速め、薬物の含量均一性を高めるための混合方法を提供する。【解決手段】 予め薬物と流動改質剤(タルク、軽質無水ケイ酸など)とを混合した後、その混合粉体とその他の添加剤とをさらに混合することによる、薬物の含量均一性を向上させる混合方法。
