A SUSTAINED RELEASE FORMULATION OF METHOTREXATE AS A DISEASE-MODIFYING ANTIRHEUMATIC DRUG (DMARD) AND AN ANTI-CANCER AGENT

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专利权人:

PACIRA PHARMACEUTICALS; INC.

发明人:

申请号：

IL222683

公开号：

IL222683A

申请日:

2012.10.25

申请国别(地区):

IL

年份:

2012

代理人:

摘要：

Disclosed is are formulations comprising a multivesicular liposome and MTX, the administration of which results in a Cmax of MTX between 5% and 50% of the Cmax of an immediate release dosage form of MTX, the duration of which lasts from about 1 to about 30 days. Also disclosed are methods of treating autoimmune diseases and cancer by administering these formulations of MTX.

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中国工程科技知识中心

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http://www.ckcest.cn/home/