Liangjin Zhu;Louie Daniel Garcia;Lois Gibson;Benjamin W. Li;William Lambert
发明人:
Louie Daniel Garcia,Lois Gibson,William Lambert,Benjamin W. Li,Liangjin Zhu
申请号：
US12914944
公开号：
US09770414B2
申请日:
2010.10.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed is are formulations comprising a multivesicular liposome and MTX, the administration of which results in a Cmax of MTX between 5% and 50% of the Cmax of an immediate release dosage form of MTX, the duration of which lasts from about 1 to about 30 days. Also disclosed are methods of treating autoimmune diseases and cancer by administering these formulations of MTX.
