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OIL-IN-WATER EMULSION COMPOSITION AND METHOD FOR PRODUCING THE SAME
专利权人:
发明人:
申请号:
EP12701727.5
公开号:
EP2667845B1
申请日:
2012.01.24
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Disclosed is an oil-in-water type emulsion composition containing a physiologically acceptable salt of a tranexamate ester and a method for producing the same. An oil-in-water type emulsion composition containing a physiologically acceptable salt of a tranexamate ester can be obtained by preparing an oil phase including: A) a physiologically acceptable salt of a tranexamate ester B) an amphiphilic substance C) an oily substance and D) water, a water-soluble organic solvent or a mixture thereof wherein the weight ratio of the ingredients A:B is in the range of 1:0.5 to 1:2.5, the weight ratio of the ingredients A:C is in the range of 1:1 to 1:5.0, and the weight ratio of the ingredients A:D is 1:0.2 to 1:5.0, and adding the oil phase to a water phase including E) water, a water-soluble organic solvent or a mixture thereof.
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