The University of British Columbia;British Columbia Cancer Agency Branch
发明人:
Raymond J. Andersen,Marianne D. Sadar,Javier Garcia Fernandez,Nasrin R. Mawji,Jun Wang,Carmen Adriana Banuelos
申请号:
US14844788
公开号:
US20160068466A1
申请日:
2015.09.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Compounds having a structure of Structure I:or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein R1, R2, R3, R4, R5, J1, J2, X, Z, n1 and n2 are as defined herein, and wherein at least one of R1, R2 or R3 is an alkyl, alkenyl, aryl or aralkyl ester, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided.