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ESTER DERIVATIVES OF ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE
专利权人:
THE UNIVERSITY OF BRITISH COLUMBIA-INDUSTRY LIAISON OFFICE;BRITISH COLUMBIA CANCER AGENCY BRANCH
发明人:
SADAR MARIANNE DOROTHY,FERNANDEZ JAVIER GARCIA,ANDERSEN RAYMOND JOHN
申请号:
AP2015008838
公开号:
AP2015008838A0
申请日:
2014.05.09
申请国别(地区):
AP
年份:
2015
代理人:
摘要:
Compounds having a structure of Structure I: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein R1, R2, R3, R4, R5, J1, J2, X, Z, n1 and n2 are as defined herein, and wherein at least one of R1, R2 or R3 is an alkyl, alkenyl, aryl or aralkyl ester, are provided. Uses of such compounds for treatment of various indications, including prostate cancer, as well as methods of treatment involving such compounds are also provided.
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