VINCENT BOUDY,PASCALE DE LONLAY DEBENEY,SANDRINE GRAFF DE FAGET,MARIE-CAROLINE HUSSON OLLAGNIER
申请号：
US14900624
公开号：
US20160136103A1
申请日:
2014.06.26
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to a pharmaceutical composition for pediatric use and having controlled release, for treating metabolic disorders involving urea in children, said composition being in the form of granules behaving like a pseudofluid, said granules including a core consisting of sucrose, cellulose or isomalt particles, and of at least one active ingredient, said active ingredient having a water solubility of 200 g/L to 630 g/L of water, and at least one coating agent covering said core, the mean diameter of the microgranules being 0.1 mm to 1.2 mm and the granules having an angle of repose of less than 30.
