BOUDY, VINCENT,DE LONLAY DEBENEY, PASCALE,GRAFF DE FAGET, SANDRINE,HUSSON OLLAGNIER, MARIE-CAROLINE
申请号：
CA2914531
公开号：
CA2914531A1
申请日:
2014.06.26
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to a pharmaceutical composition for pediatric use and having controlled release, for treating metabolic disorders involving urea in children, said composition being in the form of granules behaving like a pseudofluid, said granules including a core consisting of sucrose, cellulose or isomalt particules, and of at least one active ingredient, said active ingredient having a water solubility of 200 g/L to 630g/L of water, and at least one coating agent covering said core, the mean diameter of the microgranules being 0.1 mm to 1.2 mm and the granules having an angle of repose of less than 30°.
