The present disclosure relates to the use of nutritional compositions including lactoferrin produced by a non-human source in stimulating innate immune cells, such as macrophages, neutrophils, and dendritic cells.Cette invention concerne lutilisation de compositions nutritionnelles contenant de la lactoferrine dorigine non humaine pour stimuler les cellules immunitaires naturelles, par exemple les macrophages, les neutrophiles et les cellules dendritiques.