DYCK, BRIAN,TRAN, JOE A,TAMIYA, JUNKO,JOVIC, FLORENCE,VICKERS, TROY,CHEN, CHEN,HARRIOTT, NICOLE,COON, TIMOTHY,ASHWEEK, NEIL J
申请号：
NZ59644510
公开号：
NZ596445A
申请日:
2010.06.23
申请国别(地区):
NZ
年份:
2013
代理人:
摘要：
Disclosed herein are compounds of formula (I), wherein the variable are defined in the specification, and the use thereof in the treatment of a disease or condition mediated by modulating the activity of GPR119 in a patient. Exemplary compounds include: 2-(4-{ 4-[1-(5-ethyl-pyrimidin-2-yl)-piperidin-4-yloxyimino]-piperidin-1-yl} -2,5-difluoro-phenyl)-N-(1-methyl-piperidin-4-yl)-acetamide 4-(1-{ 4-[(2-dimethylamino-ethylcarbamoyl)-methyl]-2,5-difluoro-phenyl} -5 piperidin-4-ylideneaminooxy)-piperidine-1-carboxylic acid isopropyl ester and 1-(2-fluoro-4-methanesulfonyl-phenyl)-piperidin-4-one O-[1-(piperidine-1-carbonyl)-piperidin-4-yl]-oxime.
