Aminolipids, their synthesis and use

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专利权人:

インツェラ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング

发明人:

デイヴィッドソン・ゲーリー,レヴキン・パヴェル,リ・リンシャン,ソ・イ,ツァーナー・ダーフィト

申请号：

JP2014513927

公开号：

JP5885833B2

申请日:

2012.05.15

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The present invention provides new amino lipids and a convenient method for synthesising these compounds. These (cationic) amino lipids have good properties as transfection agents. The method is an economic versatile two step synthesis allowing the preparation of various amino lipids thus leading to the assembly of a combinatorial library of transfection agents. Moreover, the present invention provides lipid particles (liposomes) containing said amino lipids and their use for delivering bioactive agents into cells. The invention encompasses also the use of lipid particles containing the cationic amino lipids as medicament.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/