BUIST, ARJAN,BENDER, ECKHARD,MEEUSEN, TOM JULIA LEON,CLYNEN, ELKE JENNY HENRIETTE,SCHOOFS, LILIANE AMELIE HENRICA
申请号：
CA2450502
公开号：
CA2450502C
申请日:
2002.06.26
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present invention provides assays for the study of the interaction of EPFand its EPF-related peptides with a hDRR receptor. The assays are useful toidentify whether a test compound can bind to the hDRR receptor underconditions in which EPF or related peptide can bind to the receptor. Theassays are also useful to determine whether the test compound is an agonist orantagonist of hDRRs. The above assays can be performed in a variety of formatsincluding competitive, non-competitive and comparative assays in which theinteraction of EPF or EPF-related peptides with hDRRs is assessed as apositive or negative control or compared to the results obtained with the testcompound.
