Disclosed is a use of a combination package in preparation of food, medicine, health product and nutrient for improving and treating human Prader-Williy syndrome, wherein the combination package comprises the following compositions, each composition is in dosage unit form for ease of dose administration and homogeneity, and the dosage unit form is a single dose of a physical dispersion unit: the first composition comprises barley, oats, buckwheat, white beans, yellow corn, red beans, soybeans, yams, jujubes, peanuts, lotus seeds and wolfberrys; the second composition comprises bitter gourd, a soluble dietary fiber and an oligosaccharide; and the third composition comprises a soluble dietary fiber and an oligosaccharide. By means of the reasonable adjustment of diet and nutrition for patients with human Prader-Willi syndrome, this can alleviate, relieve, remedy, prevent or improve the symptoms of human Prader-Willi syndrome, and restore health.一種組合包在製備用於改善和治療人類小胖威利綜合症的食品、藥品、保健品、營養品中的應用,該組合包包括以下組合物,每種組合物為便於劑量給予和均勻性的劑量單位形式,該劑量單位形式是單一劑量的物理分散單位:第一組合物,包括:薏仁、燕麥、蕎麥、白扁豆、黃玉米、赤小豆、黃豆、山藥、大棗、花生、蓮子和枸杞;第二組合物,包括:苦瓜、可溶性膳食纖維和低聚糖;以及第三組合物,包括:可溶性膳食纖維和低聚糖。藉由對人類小胖威利綜合症患者飲食營養的合理調整,達到減輕、解除、補救、預防或改善人類小胖威利綜合症症狀,恢復健康的目的。