Gregory HINKLE,Laura SEPP-LORENZINO,Vasant JADHAV,Martin MAIER,Stuart MILSTEIN,Muthiah MANOHARAN,Kallanthottathil G. RAJEEV,M‧邁爾,Stuart MILSTEIN,S‧米爾斯泰恩,Muthiah MANOHARAN,M‧瑪諾哈蘭,Kallanthottathil G. RA
申请号:
HK18114686
公开号:
HK1255502A1
申请日:
2018.11.16
申请国别(地区):
HK
年份:
2019
代理人:
摘要:
The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the hepatitis B virus (HBV) genome, and methods of using such RNAi agents to inhibit expression of one or more HBV genes and methods of treating subjects having an HBV infection and/or HBV-associated disorder, e.g., chronic hepatitis B infection.