STRITTMATTER, WOLFGANG,HANDGRETINGER, RUPERT,SCHILBACH-STUECKLE, KARIN
申请号：
CA2940018
公开号：
CA2940018C
申请日:
2015.02.18
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The invention is directed to cancer immunotherapy. The invention is specifically directed to the induction of innate or adaptive antitumor immunity initiated by the administration of targeted IL-12 molecules preferably in conjunction with IL-2 and / or IL-7 to a cancer patient, who suffers from cancer of the muscle, bone, nerves, cartilage, tendons, blood vessels, etc., preferably from sarcoma. The invention is specifically related to the use of IL-12 in form of the specific immunoglobulin cytokine fusion protein called NHS-IL12, preferably in combination with a form of IL-2 and / or IL-7 exhibiting prolonged pharmacokinetics for the treatment of said cancer diseases.
