James Thomas Brenna,Holly Turner Reardon,Sesha Durga Kumar Kothapalli
申请号：
US14376410
公开号：
US09914969B2
申请日:
2013.01.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates methods to increase the expression of fatty acid desaturases (FADS) and increase cellular and tissue levels of highly unsaturated fatty acids (HUFA) by modulating one or more of the FADS via the action of specific classes of drugs (e.g., statins and LXR agonists). The present invention also relates to methods of treating conditions (e.g., tumor and cancer) involving deficient function of FADS by administering statins and/or LXR agonists. The present invention further relates to methods of determining the need for statins or dietary LCPUFA in subjects.
