Victoria Elizabeth Jackson,Boris Kroeplien,John Robert Porter
申请号:
US15038555
公开号:
US20160355509A1
申请日:
2014.12.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A series of substituted 3H-imidazo[4,5-c]pyridine derivatives of formula (I), being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders neurological and neurodegenerative disorders pain and nociceptive disorders cardiovascular disorders metabolic disorders ocular disorders and oncological disorders.