Sacchettini, James C.,Miller, Matthew W.,Wallis, Deeann,Zhou, Nian E.,Fossum, Theresa W.
申请号:
AU2015218949
公开号:
AU2015218949A1
申请日:
2015.02.19
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof in an amount and formulation sufficient to inhibit or induce drug-sensitization in a parasite. The methods can comprise administering a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof to a parasite in an amount and formulation sufficient to inhibit or induce drug-sensitization in the parasite.